An EC 2.3.3.* (acyltransferase converting acyl to alkyl group on transfer) inhibitor that interferes with the action of citrate (Si)-synthase, EC 2.3.3.1.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| activating transcription factor 6 | Homo sapiens (human) | Potency | 0.1157 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 0.2970 | 9 | 20 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 0.1069 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 0.0425 | 1 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 1.7415 | 2 | 6 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 0.0936 | 1 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 25.1189 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 0.9583 | 1 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 0.2459 | 8 | 21 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 1.0171 | 2 | 4 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 0.1240 | 10 | 16 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 3.2859 | 2 | 4 |
| geminin | Homo sapiens (human) | Potency | 0.1756 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 0.2118 | 2 | 4 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.0497 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 0.0410 | 2 | 4 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 77.2668 | 1 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 1.4253 | 2 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 0.0290 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 0.1493 | 3 | 5 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 84.9214 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 0.4090 | 3 | 7 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 1.1022 | 3 | 5 |
| PPM1D protein | Homo sapiens (human) | Potency | 0.0370 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 0.5705 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 0.3178 | 2 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 40.9274 | 1 | 2 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 14.6094 | 1 | 2 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 0.2907 | 2 | 4 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 0.0936 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 0.0936 | 2 | 4 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 0.2239 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 0.7816 | 2 | 4 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 37.6858 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 1.6070 | 3 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 0.3291 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 0.5795 | 3 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.0497 | 1 | 2 |